Composite
Part:BBa_K1166002:Design
Designed by: Luis Mario Leal Garza & Luis Fernando Camarillo Guerrero Group: iGEM13_TecMonterrey (2013-09-17)
HlyA-tag+Secretion system
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 1550
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 1489
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 1324
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI site found at 1306
Design Notes
HlyA C terminal part has a 5' section compatible with Silver Fusion standard. Downstream, HlyB and HlyD are both under the AraC/pBAD promoter to be induced by arabinose.
Source
The HlyB and HlyD sequences come from the parts registry, while the HlyA from the registry had mayor problems, so we took it from the genomic sequence.